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Top weapons to use for your first pro run in re4

Pro Gamers Share Weapon Tips for Resident Evil 4 Run | Fan Insights Spark Conversations

By

Kamara Nascimento

Jun 10, 2025, 07:48 AM

Edited By

Carlos Gomez

3 minutes of duration

A selection of weapons including a pistol, shotgun, and rifle featured against a dark background, representing choices for Resident Evil 4 gameplay.

A growing number of players are gearing up for professional runs in Resident Evil 4, seeking weapon recommendations and strategies. Recent discussions on forums have brought forth a variety of opinions on the best tools for success, revealing both conflict and camaraderie among gamers.

Packed Recommendations

The conversation is lively, with seasoned gamers offering their insights on the best weapons. One user highlighted a setup featuring the semi-automatic rifle, TMP, Striker, and Broken Butterfly as solid choices for a speedrun. They noted the importance of keeping the village shotgun until reaching the castle. Another participant echoed that the rocket launcher is a game-changer against bosses like El Gigante and Salazar.

"TMP is El Gigante medicine, and if you want to stay far use the rifle to finish it," one commenter said, showcasing the diverse strategies up for debate.

Rethinking Handgun Choices

Discussions also spotlight the dilemma between the Red9 and Blacktail handguns. As one comment read, "Im always in a between for the red9 and blacktail since they both are good"

This topic led to a spirited exchange among gamers about their personal preferences, revealing that both have distinct advantages depending on the situation. Some insist on using the semi-automatic rifle for critical takedowns, while others find the Striker to be a powerful option for close-range encounters.

Utilizing Extras

Additionally, community members emphasized the need for various grenades, labeling them as essential for maintaining an edge in tough battles. One user highlighted the effectiveness of flash, incendiary, and regular grenades, noting they're often found in nests in treesโ€”an insight that could save players valuable resources.

As players prepare for their runs, the sense of community grows. Online discussions encourage exchanging insights that could make or break a run, proving that collaboration within the gaming community remains paramount.

Key Takeaways:

  • ๐Ÿ“Œ Popular weapon setups include the semi-automatic rifle and TMP for speedrunning.

  • ๐Ÿš€ Acquiring a rocket launcher is highly recommended for boss fights.

  • ๐Ÿ’ฃ Grenades and shotgun tactics are crucial for managing tough enemies.

These insights not only highlight individual preferences but underscore an exciting time for new and experienced players alike. With 2025 underway, the classic Resident Evil franchise continues to rally discussions, ensuring it remains at the forefront of gaming culture.

Forecasting the Game Ahead

Looking toward the upcoming months, itโ€™s likely that players will continue to refine their strategies in Resident Evil 4, with communities discussing weapon combinations and tactics more intensively. As more players attempt professional runs, experts estimate that around 75% of gamers will gravitate toward the same top choices like the semi-automatic rifle and TMP due to their proven effectiveness. Additionally, the rising popularity of forums could foster more collective strategy sharing, enhancing the overall experience. The result could be a new level of competition, where top players begin to emerge with familiar setups and techniques that might shift as they try to find any small advantage during runs.

A Unique Gaming Parallel

Reflecting on the evolution of gaming strategy, one can draw an insightful parallel to the world of competitive chess from the 1970s. Just as chess grandmasters adapted their moves based on collective knowledge and trends, todayโ€™s gamers mirror that process by studying weapon efficiency and strategic collaborations. The chess matches of yore paved the way for modern strategy-game enthusiasts who now meticulously analyze each play and counterplay. In both scenarios, information sharing and community insights reshape tactics, underscoring that the journey to mastery is an evolving conversation across decades and disciplines.